Whereas the former mechanism acts via skin rubbing which progresses into damage, the major cause of the latter is the chemical diallyl disulfide ( DADS ), together with related compounds allyl propyl disulfide and allicin.
22.
Diallyl disulfide found in the fructans containing garlic has been shown to reduce chemical toxicity and carcinogenesis in rodents, and shows synergestic benefits with butyrate when it comes to inhibiting the growth of human cancer tumor cells in the colon.
23.
Additional studies suggest that several compounds in garlic _ allicin, ajoene and diallyl disulfide _ inhibit the chemical pathways by which the body manufactures its own cholesterol, the main source of the artery-clogging plaque that brings on heart attacks.
24.
Illustrative of its reactivity is its cyanation to allyl cyanide ( CH 2 = CHCH 2 CN ), reductive coupling to give diallyl, oxidative addition to palladium to give allylpalladium chloride dimer, ( C 3 H 5 ) 2 Pd 2 Cl 2, and dehydrohalogenation to cyclopropene.
