In contrast, the strands of a non-helical DNA duplex would be topologically non-linked, and can be separated without strand breakage.
22.
Step 3 : RecBCD continues its unwinding and moves down the DNA duplex, cleaving the 3'strand much more frequently than the 5'strand.
23.
The structure also showed the presence of so-called'acidic pins'in the centre of the tetramer, which serve to separate the DNA duplexes.
24.
Independent of the model, DNA duplexes are situated outside of the protein complex, and large movement of the protein is needed to achieve the strand exchange.
25.
Upon finding such a sequence, the single-stranded nucleoprotein filament moves into the homologous recipient DNA duplex in a process called " strand invasion ".
26.
DNA replication initially produces two catenated or linked circular DNA duplexes, each comprising one parental strand and one newly synthesised strand ( by nature of semiconservative replication ).
27.
The appeal for stacking metal ions inside a DNA duplex is the hope to obtain nanoscopic self-assembling metal wires, though this has not been realized yet.
28.
Models based on molecular mechanics calculations and recent density functional ab initio calculations support the impact of phosphate shielding at the various levels of stability of the DNA duplex.
29.
The resulting single Holliday junction then slides down the DNA duplex in the same direction in a process called branch migration, displacing the extended strand from the template strand.
30.
After the replicative helicase has unwound the parental DNA duplex, exposing two single-stranded DNA templates, replicative polymerases are needed to generate two copies of the parental genome.
