In addition, PPIF, as part of the MPTP, is involved in ischemia / reperfusion injury, traumatic brain injury ( TBI ), muscular dystrophy, and drug toxicity.
22.
Individual variation in response to drugs and in drug toxicity is a significant problem, both in clinical practice and in the development of new therapeutic agents.
23.
These projects are designed to provide data that will be used in developing predictive models for drug toxicity early on during the drug discovery and development process.
24.
He is a pioneer in the isolation, cryopreservation, and culturing of human hepatocytes and their application in the evaluation of drug metabolism, drug-drug interactions, and drug toxicity.
25.
In the FIAI trial, the researchers interpreted some abnormal lab test results as a sign that the patients were improving, when in fact the results reflected drug toxicity.
26.
In the other cases, injury from medication was traced to improper monitoring, such as a failure by the nursing staff to notice or respond to symptoms of drug toxicity.
27.
An important contributor has been the drug toxicities of several high-profile drugs believed to be caused by metabolic activation of reversible drugs ( Park et al ., 2011 ).
28.
The cause of death was a drug toxicity caused by the combination of hydromorphone ( an opiate, commonly marketed under the name Dilaudid ) and a pre-existing heart condition.
29.
By doing so, drug response rate will improve, drug toxicity will be limited and costs associated with testing various therapies and the ensuing treatment for side effects will decrease.
30.
On October 15, 2011, Anderson County coroner Greg Shore attributed the death of a South Carolina college basketball player to " drug toxicity and organ failure " caused by JWH-018.
