The frameless IUD, due to its ability to release copper from both the interior and exterior surfaces, has a high effective surface area, significantly higher than that of conventional copper IUD which allows a reduction in the overall surface area of the IUD ( nominal surface area of 200 mm2 ).
22.
A better way is to first mix the powder with hot water, so that the methyl cellulose particles are well dispersed ( and so have a much higher effective surface area ) in the water, and cool down this dispersion while stirring, leading to the much more rapid dissolution of those particles.
23.
While these beads do not have the advantage of a porous center to increase the binding capacity, magnetic beads are significantly smaller than agarose beads ( 1 to 4?m ), and the greater number of magnetic beads per volume than agarose beads collectively gives magnetic beads an effective surface area-to-volume ratio for optimum antibody binding.
24.
Bernard Soulier Syndrome is characterized by little or no expression of GPIb-IX on the surface of platelets which in turn has the same effect on GPV . There have been a number of mutations associated with BSS patients that have been mapped to GPIb?, GPIb? and GPIX demonstrating that all three subunits are required for effective surface expression of the complex on platelets.
