| 21. | Hsp72 together with Hsp90 form a heterocomplex with the estrogen receptor.
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| 22. | Hence AFPep may have utility for preventing or treating estrogen receptor-positive breast cancer.
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| 23. | AFPep also inhibits phosphorylation of the estrogen receptor and activates the phosphorylation of p53.
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| 24. | Palbociclib ( Ibrance ) is US FDA approved for estrogen receptor-positive advanced breast cancer.
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| 25. | But certain breast cancers whose cells have estrogen receptors can be fed by estrogen.
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| 26. | Ormeloxifene is a selective estrogen receptor modulator ( SERM ).
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| 27. | Anordrin is a selective estrogen receptor modulator, with both weak estrogenic and antiestrogenic properties.
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| 28. | In cases with positive estrogen receptor status antihormonal treatment is believed to improve outcome.
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| 29. | In addition, interaction with estrogen receptors has been demonstrated, leading to inhibition of function.
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| 30. | More serious adverse effects are similar to those of estrogens and estrogen receptor modulators.
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