An example of feedback inhibition in human cells is the protein aconitase ( an enzyme that catalyses the isomeration of citrate to isocitrate ).
22.
FGF15 is found in the absorptive cells of the mouse ileum and plays an important role in feedback inhibition of hepatic bile acid synthesis.
23.
Most of the pathways of amino acid biosynthesis are regulated by feedback inhibition, in which the committed step is allosterically inhibited by the final product.
24.
Each one of these pathways is regulated in a similar fashion to the common pathway; with feedback inhibition on the first committed step of the pathway.
25.
Because many hormones can produce antagonism and feedback inhibition of the synthesis of other hormones, there is significant overlap between this concept and those discussed above.
26.
The study of Merdanovic et al . suggests that the RNK activity of NadR determines NR transport and is negatively regulated by cytoplasmic NAD + feedback inhibition.
27.
The rate-limiting step occurs near the beginning of the pathway and is regulated by feedback inhibition, which ultimately controls the overall rate of the pathway.
28.
Oxaloacetate and aspartate are easily inter-convertible through a transaminase mechanism; thus high concentrations of aspartate are also a pathway of feedback inhibition of PEP carboxylase.
29.
Because leucine is synthesized by a diversion from the valine synthetic pathway, the feedback inhibition of valine on its pathway also can inhibit the synthesis of leucine.
30.
RNAs are probably not involved in sensing glucose themselves, but are more likely a part of a feedback inhibition process to regulate levels of the MsiK protein.
