In 1931, Albert Szent-Gy�rgyi and a fellow researcher Joseph Svirbely suspected that " hexuronic acid " was actually vitamin C, and gave a sample to Charles Glen King, who proved its anti-scorbutic activity in his long-established guinea pig scorbutic assay.
22.
However, in the later work which led up to the isolation of vitamin C as the antiscorbutic factor in 1932-33, Holst and Fr�lich's guinea pig model of scurvy proved to be the key biological assay which allowed identification of the chemical substance ( hexuronic acid, later called ascorbic acid ) which was ascorbutic vitamin.
23.
There, Szent-Gy�rgyi and his research fellow Joseph Svirbely found that " hexuronic acid " was actually the thus far unidentified antiscorbutic factor, known as vitamin C . After Walter Norman Haworth had determined the structure of vitamin C, and in honour of its antiscorbutic properties, it was given the formal chemical name of L-ascorbic acid.
24.
The chemical identity of King's active substance was almost identical to Szent-Gy�rgyi's hexuronic acid, but the research of S . S . Silva had declared the hexuronic acid was not vitamin C . However, within two weeks of each other in the spring of 1932, King first, and then Szent-Gy�rgyi, published articles declaring that vitamin C and hexuronic acid were indeed the same compound.
25.
The chemical identity of King's active substance was almost identical to Szent-Gy�rgyi's hexuronic acid, but the research of S . S . Silva had declared the hexuronic acid was not vitamin C . However, within two weeks of each other in the spring of 1932, King first, and then Szent-Gy�rgyi, published articles declaring that vitamin C and hexuronic acid were indeed the same compound.
26.
The chemical identity of King's active substance was almost identical to Szent-Gy�rgyi's hexuronic acid, but the research of S . S . Silva had declared the hexuronic acid was not vitamin C . However, within two weeks of each other in the spring of 1932, King first, and then Szent-Gy�rgyi, published articles declaring that vitamin C and hexuronic acid were indeed the same compound.
