One of these 3 single stranded DNA segments then invades a homologous sequence on the homologous chromosome, forming an intermediate which can be repaired through different pathways resulting either in crossovers ( CO ) or noncrossovers ( NCO ).
22.
The context specific mutation probability, the probability of observing a specific amino acid in a homologous sequence given a context, is calculated by a weighted mixing of the amino acids in the central columns of the most similar context profiles.
23.
The figure illustrates analogous double-reciprocal crossover principles for HR and RMCE, the major difference being the dramatically different requirements for homologous sequences, which are in the kb-range for HR but as short as ~ 50 bp for SSRs
24.
Homologous sequences are orthologous if they are descended from the same ancestral sequence separated by a speciation event : when a species diverges into two separate species, the copies of a single gene in the two resulting species are said to be orthologous.
25.
He found in particular that the narcotic effect of aliphatic spirits in the homologous sequence increases with the growth of the number of carbon atoms in their molecules, and that the effect of sugar on the heart depends on its stereo chemical structure.
26.
RNA silencing pathways are associated with the regulatory activity of small non-coding RNAs ( approximately 20 30 nucleotides in length ) that function as factors involved in inactivating homologous sequences, promoting endonuclease activity, translational arrest, and / or chromatic or DNA modification.
27.
For example, Pfold is used in secondary structure prediction from a group of related RNA sequences, covariance models are used in searching databases for homologous sequences and RNA annotation and classification, RNApromo, CMFinder and TEISER are used in finding stable structural motifs in RNAs.
28.
A key similarity between prokaryotic sex and eukaryotic sex is that DNA originating from two different individuals ( parents ) join up so that homologous sequences are aligned with each other, and this is followed by exchange of genetic information ( a process called genetic recombination ).
29.
In 2011, a different, and this time " global " statistical approach, demonstrated that predicted coevolved residues were sufficient to predict the 3D fold of a protein, providing there are enough sequences available ( > 1, 000 homologous sequences are needed ).
30.
Here, p _ { ij } is the probability of two amino acids i and j replacing each other in a homologous sequence, and q _ i and q _ j are the background probabilities of finding the amino acids i and j in any protein sequence.
