A small percentage of hydatidiform moles have biparental diploid genomes, as in normal living persons; they have two sets of chromosomes, one inherited from each biological parent.
22.
The initial clinical diagnosis of GTD should be confirmed histologically, which can be done after the evacuation of pregnancy ( see �Treatment?below ) in women with hydatidiform mole.
23.
In 2 to 3 % of cases, hydatidiform moles may develop into choriocarcinoma, which is a malignant, rapidly growing, and metastatic ( spreading ) form of cancer.
24.
She was 13 weeks pregnant when a visit to her ob-gyn revealed she had a hydatidiform mole, a pregnancy-related chromosomal mix-up that results in a benign tumor.
25.
The prognosis of hydatidiform moles can be estimated by scoring systems such as the " Modified WHO Prognostic Scoring System ", wherein scores between 1 and 4 from various parameters are summed together:
26.
Complete hydatidiform moles have no fetal tissue and no maternal DNA, as a result of a maternal ovum with no functional DNA . Most commonly, a single spermatozoon duplicates and fertilises an empty ovum.
27.
Based on morphology, hydatidiform moles can be divided into two types : in " complete moles ", all the chorionic villi are vesicular, and no sign of embryonic or fetal development is present.
28.
Hydatidiform moles are a common complication of pregnancy, occurring once in every 1000 pregnancies in the US, with much higher rates in Asia ( e . g . up to one in 100 pregnancies in Indonesia ).
29.
Gestational trophoblastic disease like hydatidiform moles ( " molar pregnancy " ) or choriocarcinoma may produce high levels of ?hCG ( due to the presence of syncytialtrophoblasts-part of the villi that make up the placenta ) despite the absence of an embryo.
30.
Detection of this hormone in urine or conception . hCG is also an important tumor marker because it is produced by some kinds of tumor, such as : seminoma, choriocarcinoma, germ cell tumors, hydatidiform mole formation, teratoma with elements of choriocarcinoma, and islet cell tumor
