8-Hydroxyquinoline has been identified as a main allelopathic compound produced by diffuse knapweed ( " C . diffusa " ); native North American plants are typically sensitive to it, while those of Eastern Europe and Asia Minor usually have coevolved with the knapweed and are little harmed if at all, aided by native microorganisms that break down or even feed on the abundantly secreted compound.
22.
Baba " et al . " showed that many quinoline derivatives show promise in their anti-inflammatory effects for the treatment of arthritis, Schmidt " et al . " delved into the progress behind treating drug-resistant malaria using 4-hydroxyquinoline derivatives, and Lui-Zai Gang " et al . " studied the use of quinoline derivatives as HIV-1 integrase inhibitors.