Hyperinsulinism due to diffuse overactivity of beta cells, such as in many of the forms of congenital hyperinsulinism, and more rarely in adults, can often be treated with diazoxide or a somatostatin analog called octreotide.
22.
Hyperinsulinism due to diffuse overactivity of beta cells, such as in many of the forms of congenital hyperinsulinism, and more rarely in adults, can often be treated with diazoxide or a somatostatin analog called octreotide.
23.
In addition to being a risk factor for type 2 diabetes, hyperinsulinism due to insulin resistance may increase blood pressure and contribute to hypertension by direct action on vascular endothelial cells ( the cells lining blood vessels ).
24.
The treatment of this form of hyperinsulinism depends on the cause and the severity of the hyperinsulinism, and may include surgical removal of the source of insulin, or a drug such as diazoxide or octreotide that reduces insulin secretion.
25.
The treatment of this form of hyperinsulinism depends on the cause and the severity of the hyperinsulinism, and may include surgical removal of the source of insulin, or a drug such as diazoxide or octreotide that reduces insulin secretion.
26.
By the 1970s, nesidioblastosis was primarily used to describe the pancreatic dysfunction associated with persistent congenital hyperinsulinism and in most cases from the 1970s until the 1980s, it was used as a synonym for what is now referred to as congenital hyperinsulinism.
27.
By the 1970s, nesidioblastosis was primarily used to describe the pancreatic dysfunction associated with persistent congenital hyperinsulinism and in most cases from the 1970s until the 1980s, it was used as a synonym for what is now referred to as congenital hyperinsulinism.
28.
A meter can occasionally be useful in the monitoring of severe types of hypoglycemia ( e . g ., congenital hyperinsulinism ) to ensure that the average glucose when fasting remains above 70 mg / dl ( 3.9 mmol / l ).
29.
Subsequently alterations of Pedersen's Hypothesis took place : Nutrients other than sugar and their linkage to fetal overgrowth in diabetic pregnancy were taken into account too; but the crucial role of the fetal hyperinsulinism and monitoring of motherly glucose was nevertheless stressed.
30.
In an article entitled " The surgical therapy of hyperinsulinism ", in " J Internat Chir " 3 : 237-276 ( 1938 ), he proposed that no pancreatic surgery to look for an insulinoma be performed unless these criteria were met.