Quantum chemical effects like group-group interactions, mesomeric effects and inductive effects also are incorporated into COSMO-RS by this approach.
22.
Interestingly, due to the inductive effect, water molecules are actually MORE attracted to fat molecules than the fat molecules are to each other.
23.
This is purely for the inductive effect, so take meta-fluorobenzene as an example or something ( but I meant EWGs in general ).
24.
As the induced change in polarity is less than the original polarity, the inductive effect rapidly dies out and is significant only over a short distance.
25.
Heteroatom-containing substituents may direct metalation to the benzylic site closest to the heteroatom or increase the acidity of the ring carbons via an inductive effect.
26.
The differences in reduction potentials is attributed in the cobaltocenium system to the inductive effect of the alkyl groups, further stabilising the 18-valence electron species.
27.
Moreover, the inductive effect is permanent but feeble since it involves the shift of strongly held ?-bond electrons and other stronger factors may overshadow this effect.
28.
:: : Uric acid has many more oxygens and nitrogens that phthalimide, so i suspect that the inductive effect has a whole lot to do with it.
29.
My hypothesis is that the inductive effect is also at play, where having a carbanion resonance structure next to a ( protonated ) oxygen atom will stabilise it somewhat.
30.
These substituents stabilize the negative charge on the carboxylate oxygen atom by an electron-withdrawing inductive effect (-I ) and also by a negative mesomeric effect (-M ).
