| 21. | PKM2 is an isozyme of pyruvate kinase that is responsible for the Warburg effect in cancer cells.
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| 22. | This protein, which is an isozyme of ROCK1 is a target for the small GTPase Rho.
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| 23. | It is an inhibitor of cytochrome P450 CYP2D6 and may interfere with other drugs metabolized by this isozyme.
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| 24. | For those diagnosed with essential pentosuria, the major isozyme appears to be the same as the minor one.
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| 25. | This isozyme is ubiquitously expressed in adult human tissues, including liver, brain, kidney, and spleen.
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| 26. | This isozyme is highly expressed in brain, and preferentially utilizes myristate, arachidonate, and eicosapentaenoate as substrates.
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| 27. | This may be compounded by the fact that dextromethorphan and chlorpheniramine are both metabolized by CYP2D6 isozyme of Cytochrome P450.
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| 28. | Meanwhile, the muscle isozyme plays a major role in the cellular response to long-term adaptation to hypoxia.
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| 29. | L-xylulose reductase, contained in red blood cells, is composed of both a major and minor isozyme.
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| 30. | The human 17?-HSD1 isozyme is highly specific for estrogens over androgens whereas the rodent isozyme is less specific.
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