Although lung biopsy is usually not necessary, the presence of asbestos bodies in association with pulmonary fibrosis establishes the diagnosis.
22.
Definitive diagnosis of berylliosis is based on history of beryllium exposures, documented beryllium sensitivity and granulomatous inflammation on lung biopsy.
23.
In cases where a lung biopsy is indicated, a trans-bronchial biopsy is usually unhelpful, and a surgical lung biopsy is often required.
24.
In cases where a lung biopsy is indicated, a trans-bronchial biopsy is usually unhelpful, and a surgical lung biopsy is often required.
25.
Small biopsies, such as those obtained via transbronchial lung biopsy ( performed during bronchoscopy ) are usually not sufficient for this purpose.
26.
Given the invasive nature of a lung biopsy diagnosis can also be based on clinical history consistent with berylliosis, abnormal pulmonary function tests.
27.
The only way to diagnose this condition is by doing a lung biopsy as chest x-rays and CT scans come back as normal.
28.
Video-assisted thoracoscopic lung biopsy is the most definitive technique, but transbronchial biopsy has a yield of over 50 % and can also be effective.
29.
In the right clinical setting, it is possible to make the diagnosis of IPF by HRCT alone, obviating the need for surgical lung biopsy.
30.
Scanning tests themselves have a downside, because they lead to " overdetection " _ and risky surgeries and lung biopsies for benign conditions, experts say.
