Main scientific contributions include designing and introducing into clinical practice the surgical lympho-venous shunts ( 1966 ), discovery of spontaneous rhythmic lymphatic contractility in humans ( 1980 ), proving that bacterial factor is responsible for development of human limb lymphedema ( 1994 ), introducing low-dose, long-term penicillin administration for prevention of chronic dermatitis and lymphangitis in Asian countries ( 1996 ), detecting the phenomenon of non-specific elimination of cell grafts ( 1990 ), preservation of tissues for transplantation in dehydrating sodium chloride ( 2003 ).
