| 21. | While corticosteroids with mineralocorticoid activity may help prevent vasospasm their use does not appear to change outcomes.
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| 22. | Mineralocorticoid hormones are synthesized in the outermost layer of the adrenal cortex known as the zona glomerulosa.
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| 23. | A genetically inherited deficiency of HSD11B2 is the underlying cause of the syndrome of apparent mineralocorticoid excess.
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| 24. | Glucocorticoids are distinguished from mineralocorticoids and sex steroids by their specific receptors, target cells, and effects.
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| 25. | Management is similar to that of 21-hydroxylase deficient CAH except that mineralocorticoids need not be replaced.
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| 26. | It also catalyzes the conversion of 11-deoxycorticosterone ( DOC ) to corticosterone in the mineralocorticoid pathway.
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| 27. | Mineralocorticoids are replaced in all infants with salt-wasting and in most patients with elevated renin levels.
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| 28. | Mineralocorticoid receptor blockers, such as spironolactone, coupled with potassium supplementation are the most commonly used treatments.
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| 29. | Fluorines also find their uses in common mineralocorticoids, a class of drugs that increase the blood pressure.
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| 30. | Amlodipine has additionally been found to act as an antagonist of the mineralocorticoid receptor, or as an antimineralocorticoid.
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