Global replacement of all hydrogens in muscone was achieved by heating muscone with Rh / C in D 2 O at 150 �C . It was found that the human musk-recognizing receptor, OR5AN1, identified using a heterologous olfactory receptor expression system and robustly responding to muscone, fails to distinguish the so-prepared isotopomers of muscone in vitro.
22.
Global replacement of all hydrogens in muscone was achieved by heating muscone with Rh / C in D 2 O at 150 �C . It was found that the human musk-recognizing receptor, OR5AN1, identified using a heterologous olfactory receptor expression system and robustly responding to muscone, fails to distinguish the so-prepared isotopomers of muscone in vitro.
