| 21. | Yet, the Pitx 2 pathway is PAX3 dependent and requires this gene to enact limb myogenesis.
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| 22. | It accomplishes this by repressing MyoD transcription by binding to the enhancer region, and prevents premature myogenesis.
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| 23. | Pax7 is a transcription factor that plays a role in myogenesis through regulation of muscle precursor cells proliferation.
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| 24. | A lack of c-Met disrupts secondary myogenesis and as in LBX1 prevents the formation of limb musculature.
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| 25. | These consequences further reveal the complexity of myogenesis and the importance of each genetic factor in proper muscle development.
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| 26. | Pitx2 can determine the development and activation of the MyoD gene ( the gene responsible for skeletal myogenesis ).
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| 27. | Calponin 3 is also present in embryonic trophoblasts and myoblasts with functions in cell fusion during embryonic development and myogenesis
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| 28. | Skeletal myogenesis depends on the strict regulation of various gene subsets in order to differentiate the myogenic progenitors into myofibers.
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| 29. | This has also revealed the significance of PAX3 in myogenesis, and that it ensures the survival of myogenic progenitors.
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| 30. | Calponin 3 has been shown to participate in actin cytoskeleton-based activities such as that in embryonic development and myogenesis.
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