Vasodilators such as sodium nitroprusside can be considered for patients with ongoing hypertension, but they should never be used alone, as they generally cause reflex tachycardia.
22.
Many drugs are mimics or prodrugs of natural nitrogen-containing signal molecules : for example, the organic nitrates nitroglycerin and nitroprusside control blood pressure by metabolizing into nitric oxide.
23.
Hypertension presents a risk for intracranial hemorrhage ( i . e ., bleeding in the brain ) and, if severe, is typically treated with intravenous phentolamine or nitroprusside.
24.
Sodium nitroprusside is also used in microbiology, where it has been linked with the dispersal of " Pseudomonas aeruginosa " biofilms by acting as a nitric oxide donor.
25.
Blood pressure can be lowered either with a combination of alpha blockers and beta blockers ( or a mixed alpha / beta blocker ), or with other drugs such as nifedipine or nitroprusside.
26.
The ECLIPSE trials consisted of three safety trials in which 1506 patients were randomized to receive Cleviprex, nitroglycerin, sodium nitroprusside, or nicardipine, for the treatment of hypertension associated with cardiac surgery.
27.
Sodium nitroprusside, a very potent, short-acting vasodilator, is most commonly used for the quick, temporary reduction of blood pressure in emergencies ( such as malignant hypertension or aortic dissection ).
28.
Analysis of the clear solution by GC / MS and color testing ( Marquis ( brown ) and nitroprusside ( negative ) ) confirmed DMT in naphtha ( not quantitated, but again estimated to be roughly 5 percent ).
29.
The test, called Simon's test, is performed by adding 1 volume of a solution of sodium nitroprusside and acetaldehyde in deionized water to a suspected drug, followed by the addition of 2 volumes of an aqueous sodium carbonate solution.
30.
The vasodilatation caused by sodium nitroprusside has been shown to be mediated not only by NO generation, but also by endogenous cyanide generation, which adds not only toxicity, but also some additional antihypertensive efficacy compared to nitroglycerine and other non-cyanogenic nitrates which do not cause blood cyanide levels to rise.
