When the recombinant MBP includes a signal peptide, the fusion protein can be exported into the periplasmic space, which facilitate its purification since the periplasmic fluid contains only a limited number of proteins and can be recovered either by an osmotic shock or by permeabilization of the outer membrane with antibiotics, e . g.
22.
Taurine crosses the blood brain barrier and has been implicated in a wide array of physiological phenomena including inhibitory neurotransmission, long-term potentiation in the striatum / hippocampus, membrane stabilization, feedback inhibition of neutrophil / macrophage respiratory burst, adipose tissue regulation and possible prevention of obesity, calcium homeostasis, recovery from osmotic shock, protection against glutamate excitotoxicity and prevention of epileptic seizures.
