In the meantime, a variety of theories of inheritance ( based on pangenesis, orthogenesis, or other mechanisms ) were debated and investigated vigorously.
22.
In May 1865 he sent a manuscript to his friend Thomas Huxley outlining his theory which he called pangenesis and asking whether he should publish it.
23.
Darwin's hereditary mechanism Darwin hypothesized of pangenesis that supported gradualism also lacked any supporting evidence and was disputed by the empirical tests of Francis Galton.
24.
The Irish physician Henry Freke in his book " Origin of Species by Means of Organic Affinity " ( 1861 ) developed a variant of pangenesis.
25.
A very similar hypothesis to Darwin's pangenesis was held by the French naturalist Georges-Louis Leclerc, Comte de Buffon who developed a system of heredity.
26.
In 1875 a second edition was published in which Darwin made a number of corrections and also reworked Chapter XI on Bud-variation and Chapter XXVII on Pangenesis.
27.
Other theories included the pangenesis of Charles Darwin ( which had both acquired and inherited aspects ) and Francis Galton's reformulation of pangenesis as both particulate and inherited.
28.
Other theories included the pangenesis of Charles Darwin ( which had both acquired and inherited aspects ) and Francis Galton's reformulation of pangenesis as both particulate and inherited.
29.
Darwin wrote that Hippocrates'pangenesis was " almost identical with mine merely a change of terms and an application of them to classes of facts necessarily unknown to the old philosopher ."
30.
He did in fact suggest such a mechanism, called pangenesis, based on gemmules transported in the bloodstream, but subsequent experiments by Francis Galton showed that this proposed mechanism was incorrect.
