Additionally, the following side effects have all been reported by patients : Chronic muscular pain, numbness and weakness of the limbs, Horner's Syndrome, anhidrosis ( inability to sweat ), hyperthermia ( exacerbated by anhidrosis and systemic thermoregulatory dysfunction ), neuralgia, paraesthesia, fatigue and amotivationality, breathing difficulties, substantially diminished physiological / chemical reaction to internal and environmental experience ( e . g . pleasure and pain / perceptual stimuli ), somatosensory malfunction, aberrant physiological reaction to stress and exertion etc ., Reynaud s disease ( ironically a possible indication for surgery ), reflex hyperhidrosis, altered / erratic blood pressure and circulation, defective fight or flight response system, loss of adrenaline, eczema and other skin conditions resulting from exceptionally dry skin; rhinitis, gustatory sweating ( also known as Frey's syndrome ).
