Flammer is a glaucoma specialist who developed a new pathogenetic concept of glaucomatous damage according to which unstable blood supply leads to oxidative stress, which in turn plays a major role in apoptosis ( cell death ) of cells in optic nerve and retina in glaucoma patients.
22.
In the Homeopathic Pathogenetic Trial of the alkaloids Capsaicin and Dihydrocapsaicin, the interesting finding was that about 40 % of the healthy volunteers produced symptoms pertaining to pain, with high-dilution, potentised medicine from the source materials which has known capacity to produce pain in crude form.
23.
"NC A & T-a biomaterial that can be used in packaging and on surfaces to prevent the spread of norovirus, one of the most common causes of foodborne illness in the United States, and the discovery that extracts from bitter melon and sorrel in lab tests can reduce pathogenetic virulence.
24.
After receiving a master's degree in business management in 1990, Knox entered the Medical College of Wisconsin's graduate pathology program as a doctoral student in 1992, where she investigated the pathogenetic interactions between HIV and HHV-6 as her doctoral dissertation research project under Donald Carrigan with whom she collaborated on various publications during the period.
25.
Endogenous sulfur dioxide also has been shown to lower the proliferation rate of endothelial smooth muscle cells in blood vessels, via lowering the MAPK activity and activating adenylyl cyclase and protein kinase A . Smooth muscle cell proliferation is one of important mechanisms of hypertensive remodeling of blood vessels and their stenosis, so it is an important pathogenetic mechanism in arterial hypertension and atherosclerosis.
26.
In 2007, the Foundation funded the expansion of the Saint Francis Health System to include two new facilities : Saint Francis Hospital South, a 96-bed hospital to accommodate the growing population in the southern part of Tulsa; and the Laureate Institute for Brain Research, a clinical neuroscience research institute dedicated to expanding the knowledge about the underlying pathogenetic features of mental disorders.
27.
According to the most recent findings, however, the development of fibroblastic foci precedes the accumulation of inflammatory cells and the consequent deposition of collagen . alt = Etiology and pathobiology of Idiopathic Pulmonary Fibrosis ( IPF ) This pathogenetic model is indirectly supported by the clinical features of IPF, including an insidious onset, progression over several years, relatively infrequent acute exacerbations, and failure to respond to immunosuppressive therapy.
28.
Biochemical and mitochondrial morphological studies on cells from patients affected by autosomal dominant optic atrophy have shown a severe defect in the shape ( with a very remarkable fragmentation of the mitochondrial tubules in small spheres ) and distribution of mitochondria, occurring independently from a bioenergetic defect ( respiratory chain function, ATP synthesis, and reactive oxygen species production ) or apoptosis, indicating that the mitochondrial fusion defect is the primary pathogenetic mechanism, although variable bioenergetic defects can also occur as a secondary phenomenon, especially in severe cases with complicated phenotypes and accumulation of multiple mitochondrial-DNA deletions.
29.
The book lists the health effects of 27 drugs in common use as recorded in the medical literature along with Hahnemann's own observations from taking the drugs himself : " The first collection of the effects of medicines . . . according to his own observations and those of others was, as is well known, published in the work, Fragmenta de viribus medicamentorum, 1805 . " These were " medicinal substances whose pure pathogenetic action he had ascertained by experiments on himself, his family, and a few friends . " The book makes no mention of homeopathy or any theories of cure and makes no claims about their uses.
