21. He was rapidly losing weight and shortly after the tour was diagnosed with pemphigus vulgaris, a rare autoimmune disease. 22. Recently, Rituximab, an anti-CD20 antibody, was found to improve otherwise untreatable severe cases of Pemphigus vulgaris. 23. Abnormal distribution of plakoglobin due to mutations in genes encoding for Desmoglein 1 and 3 have also been implicated in Pemphigus vulgaris. 24. However, T-cells and CD56 + Natural Killer cells have also been postulated to be associated effectors of paraneoplastic pemphigus . 25. While serving on the front in Russia in 1915, he began to suffer from a rare and painful skin disease called pemphigus . 26. Left untreated, pemphigus foliaceus in animals is life-threatening, leading to not only loss of condition but also secondary infection. 27. Her disease _ pemphigus _ is serious and long-term, and her weakened immune system means she is susceptible to other sicknesses. 28. Epidermolysis Bullosa, Epidermolysis Bullosa Acquisita, Erythema Multiforme, Lichen Planus, pemphigus vulgaris, Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis. 29. Other example vesiculobullous diseases include pemphigus vulgaris, mucous membrane pemphigoid, bullous pemphigoid, dermatitis herpetiformis, linear IgA disease, and epidermolysis bullosa. 30. In 1964, researchers found that the blood of patients with pemphigus contained antibodies to the layers of skin that separate to form the blisters.
