Some studies indicate that hypertension can develop when there are no organic osmolytes ( i . e . TMAO ) that can counteract an increase in osmotic pressure and peripheral resistance.
22.
The decrease in angiotensin II results in relaxation of arteriole smooth muscle leading to a decrease in total peripheral resistance, reducing blood pressure as the blood is pumped through widened vessels.
23.
Sympathetic activation leads to an elevation of total peripheral resistance and cardiac output via increased contractility of the heart, heart rate, and arterial vasoconstriction, which tends to increase blood pressure.
24.
Eventually, the peripheral resistance to the action of insulin becomes so great that even with maximal insulin production the body doesn't respond enough to keep the blood sugar level normal.
25.
Specifically, in response to stress in a subject with central obesity the cardiac output dependent pressor response is shifted toward a generalised rise in peripheral resistance with an associated decrease in cardiac output.
26.
Individuals with deficient FMO3 activity have a higher prevalence of hypertension and other cardiovascular diseases, since there is a decrease in formation of TMA N-oxides to counterbalance the effects of a higher osmotic pressure and peripheral resistance.
27.
Between 1912 and 1925 he published articles analyzing the contractile properties of isolated blood vessels, the mechanism of the Korotkoff sounds, the effect of peripheral resistance on blood pressure, and blood pressure measurements in normal and pathological conditions.
28.
These putative effects can be taken in context of a wide range of cardiovascular phenomena regulated by the endocannabinoid system and an overall role of cannabis in causing decreased peripheral resistance and increased cardiac output, which potentially could pose a threat to those with cardiovascular disease.
29.
Blood pressure in the arteries supplying the body is a result of the work needed to pump the cardiac output ( the flow of blood pumped by the heart ) through the " vascular resistance ", usually termed total peripheral resistance by physicians and researchers.
30.
For example, during vasoconstriction the end diastolic volume ( EDV ) will increase due to an increase in TPR ( total peripheral resistance ) ( increased TPR causes a decrease in the stroke volume which means that more blood will be left in the ventricle upon contraction an increased end systolic volume ( ESV ).
