The final step involves reacting this product with BH3 in THF, then reacting the product with piperazine in MeOH at reflux.
22.
Prior to development of these drugs, during the 1950s and 1960s, treatment with piperazine, dichlorvos and trichlorfon was used.
23.
In October 2009, it was announced that from 23 December 2009, BZP and related piperazines would be Misuse Of Drugs Act.
24.
Piperazine ( PZ ) reacts with carbon dioxide to produce PZ carbamate and PZ bicarbamate at low loading and operating range, respectively.
25.
"' Estropipate "'( salt of estrone sulfate and piperazine, and is hydrolyzed into estrone in the body.
26.
"' Ipsapirone "'is a 5-HT 1A receptor partial agonist of the piperazine and azapirone chemical classes.
27.
Various cyclic amine groups can act as the basic moiety and potency stays relatively unchanged for example aryl piperazine, piperidine and morpholine.
28.
This is the date BZP and piperazine analogs become illegal in the federal schedules which are now enacted by all Australian states and territories.
29.
Cinepazide was discovered by scientists at Laboratoires Delalande ( now part of Sanofi ) in 1969 in an effort to explore useful substituted cinnamoyl-piperazine compounds.
30.
It is closely related to several other piperazines, including eltoprazine and batoprazine, and TFMPP, as well as more distantly to the azapirones such as buspirone.
