Production of T 3 and its prohormone thyroxine ( T 4 ) is activated by thyroid-stimulating hormone ( TSH ), which is released from the anterior pituitary gland.
22.
Another prohormone convertase, proprotein convertase 2 plays a more minor role in the first step of insulin biosynthesis, but a greater role in the first step of glucagon biosynthesis.
23.
The physiological activity of thyroid hormone is regulated by a system of enzymes that activate, inactivate or simply discard the prohormone T 4 and in turn functionally modify T 3 and rT 3.
24.
Both neuropeptides and peptide hormones are synthesized by the same sets of enzymes, which include prohormone convertases and carboxypeptidases that selectively cleave the peptide precursor at specific processing sites to generate the bioactive peptides.
25.
Removal of the 19-amino acid N-terminal signal peptide generates the prohormone, which is hydrolysed to AVT ( derived from amino acids 20-28 ) and neurophysin VT ( derived from amino acids 32-161 ).
26.
As such 17?-hydroxypregenolone represents an intermediary in the ? 5 pathway that leads from pregnenolone to DHEA . 17?-Hydroxypregneolone is also converted to 17?-hydroxyprogesterone, a prohormone for glucocorticosteroids and androstenedione through the activity of 3?-hydroxysteroid dehydrogenase.
27.
The FNDC5 gene encodes a prohormone, a single-pass type I membrane protein ( human, 212 amino acids; mouse and rat, 209 amino acids ) that is upregulated by muscular exercise and undergoes post-translational processing to generate irisin.
28.
Although CDMA was sold as a " prohormone " or " prosteroid " of chlorodehydromethyltestosterone ( CDMT ), it is likely that the conversion is far from complete and that much of the activity of the drug may be attributable to its unchanged form.
29.
In 2001 Arnold's company introduced the prohormone 1-Androstenediol, under the marketing name 1-AD . Like andro, 1-AD is a prohormone that is easily converted by the body into 1-testosterone, and it sold well.
30.
In 2001 Arnold's company introduced the prohormone 1-Androstenediol, under the marketing name 1-AD . Like andro, 1-AD is a prohormone that is easily converted by the body into 1-testosterone, and it sold well.
