| 21. | Common sources are phosphoenol pyruvate, acetyl phosphate, and creatine phosphate.
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| 22. | The first four MCT isoforms are responsible for pyruvate / lactate transport.
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| 23. | It is converted into fumarate and pyruvate by 3-fumarylpyruvate hydrolase.
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| 24. | It activates pyruvate dehydrogenase phosphatase which in turn activates the pyruvate dehydrogenase complex.
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| 25. | It activates pyruvate dehydrogenase phosphatase which in turn activates the pyruvate dehydrogenase complex.
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| 26. | Serine is then converted to pyruvate by serine dehydratase.
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| 27. | The areas surrounding the phosphorylation sites on pyruvate dehydrogenase are shown in red.
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| 28. | Here, it is decarboxylated to produce and pyruvate.
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| 29. | Pyruvate carboxylase deficiency is an inherited metabolic disorder where anaplerosis is greatly reduced.
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| 30. | Mutations in the " PC " gene cause pyruvate carboxylase deficiency.
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