A number of anti-malarial compounds ( chloroquine, hydroxychloroquine, mefloquine, quinine, quinidine ) cause phospholipidosis, myopathy and neurological damage.
22.
Escitalopram is a substrate of P-glycoprotein and hence P-glycoprotein inhibitors such as verapamil and quinidine may improve its blood-brain penetrability.
23.
Both propoxyphene and norpropoxyphene are potent blockers of cardiac membrane sodium channels and are more potent than lidocaine, quinidine, and procainamide in this respect.
24.
Additionally there is an increase the risk of cardiotoxicity and arrhythmias when co administered with drugs such as Dihydroquinidine barbiturate, Quinidine, and Quinidine barbiturate.
25.
Additionally there is an increase the risk of cardiotoxicity and arrhythmias when co administered with drugs such as Dihydroquinidine barbiturate, Quinidine, and Quinidine barbiturate.
26.
At micromolar concentrations, quinidine inhibits Na + / K +-ATPase by binding to the same receptor sites as the digitalis glycosides such as ouabain.
27.
However, the use of quinidine to treat arrhythmia really only came into its own because a physician listened to the astute observation of one of his patients.
28.
Other drugs that prolong the QT interval such as quinidine, verapamil, amiodarone, sotalol and methadone may also interact with chlorpromazine to produce additive QT interval prolongation.
29.
This gene may play a role in malignancies and disease that involve this region as well as the transport of chloroquine-and quinidine-related compounds in the kidney.
30.
Four years later, Walter von Frey of Berlin reported in a leading Viennese medical journal that quinidine was the most effective of the four principal cinchona alkaloids in controlling atrial arrhythmias.
