Research at the preclinical ( animal ) stage include a new compound that can remove lipofuscin from retinal pigment epithelial cells.
22.
Once transported, ATR is reduced to vitamin A and then transferred to retinal pigment epithelium to be recycled into 11-" cis "-retinal.
23.
RGR-opsin is exclusively expressed in tissue close to the rods and cones, the retinal pigment epithelium ( RPE ) and M�ller cells.
24.
This paper relates how he and his colleagues discovered that NPD1 arrests apoptosis in retinal pigment epithelial cells at the pre-mitochondrial level.
25.
AMD-like pathology begins with small yellow deposits ( drusen ) in the macula, between the retinal pigment epithelium and the underlying choroid.
26.
Emixustat hydrochloride is a non-retinoid small molecule inhibitor of RPE65 ( retinal pigment epithelium-specific 65 kDa protein, also known as retinoid isomerohydrolase ).
27.
It is an inheritable classical Mendelian type X-linked recessive disorder wherein the retinal pigment epithelium lacks pigment while hair and skin appear normal.
28.
The outer layer is highly pigmented, continuous with the retinal pigment epithelium, and constitutes the cells of the iris, where it takes on pigment.
29.
When researchers treated Stargardt disease-afflicted mice with a lentiviral vector containing a functional " ABCA4 " gene, A2E buildup in the retinal pigment epithelium decreased.
30.
The optic vesicles then develop into the optic cup with the inner layer forming the retina and the outer portion forming the retinal pigment epithelium.
