This gene encodes a member of the pancreatic-type of secretory ribonucleases, a subset of the ribonuclease A superfamily.
22.
It is a potent inhibitor of ribonuclease and topoisomerase II by preventing the binding of the nucleic acid to the enzyme.
23.
Specifically, Anfinsen established how the protein enzyme ribonuclease folds to obtain the characteristic three-dimensional structure that determines its function.
24.
Such proteins interact with bilayers only electrostatically, for example, ribonuclease and poly-lysine interact with membranes in this mode.
25.
Other examples of physiological enzyme inhibitor proteins include the barstar inhibitor of the bacterial ribonuclease barnase and the inhibitors of protein phosphatases.
26.
"' ZC3H12B "'contains a ribonuclease domain, as well as a CCCH-type zinc finger domain.
27.
These studies revealed the subunit structure of the enzyme and helped define the polymerase and Ribonuclease H activities inherent with that enzyme.
28.
Multiple in vitro substrates for thioredoxin have been identified, including ribonuclease, choriogonadotropins, coagulation factors, glucocorticoid receptor, and insulin.
29.
Side view of porcine ribonuclease inhibitor; ribbon is colored from blue ( N-terminus ) to red ( C-terminus ).
30.
Human Drosha was cloned in 2000, when it was identified as a nuclear dsRNA ribonuclease involved in the processing of ribosomal RNA precursors.
