The testicles converge to form the seminiferous tubules, coiled tubes at the top and back of each testicle.
22.
Spermatogonia stem cells in mammals are found between the basal membrane of the seminiferous tubules and the Sertoli cells.
23.
They secrete testis-determining factor, a binding protein which increases the concentration of testosterone inside the seminiferous tubules.
24.
The reconstruction of these junctions is important because it facilitates the migration of the developing germ cells across the seminiferous epithelium
25.
The ampullae are otherwise essentially identical to the seminiferous tubules in higher vertebrates, including the same range of cell types.
26.
However, an even larger difference is seen in how many of the seminiferous tubules in the testes contain mature sperm;
27.
In 1979, Levin described germinal cell aplasia with focal spermatogenesis where a variable percentage of seminiferous tubules contain germ cells.
28.
Furthermore, loss of GPR56 leads to reduced fertility in male mice, resulting from a defect in seminiferous tubule development.
29.
These data suggested that cypermethrin can induce impairments of the structure of seminiferous tubules and spermatogenesis in male rats at high doses.
30.
In males, this process is known as spermatogenesis and takes place only after puberty in the seminiferous tubules of the testes.
