This gene encodes a DEAD box protein, which is an RNA-dependent ATPase, and also a proliferation-associated nuclear antigen, specifically reacting with the simian virus 40 tumor antigen.
22.
When the vaccine was squirted into human mouths, the simian virus could have passed through a sore or ulcer and entered the bloodstream, subsequently to evolve into HIV-1.
23.
"Good breeder . " ) To engineer her mutants, she injects embryos with a lethal monkey virus, Simian Virus 40; it triggers cancerous tumors almost identical to those in humans.
24.
It binds to and alkylates DNA, resulting in a reduction of both cellular and simian virus 40 ( SV40 ) DNA replication which ultimately reduces the rate of cancer growth.
25.
Also, for a few specific diseases, the relevant pathogens may be found in the urine; for example : Leptospira interrogans, Salmonella typhi, Salmonella paratyphi, Schistosoma haematobium, BK virus or Simian virus.
26.
In January, 1997, at the age of 89, Ratner traveled to Bethesda, Maryland to attend a workshop of the National Institutes of Health entitled Simian Virus 40 : A Possible Human Polyomavirus.
27.
The possibility of a cancer connection has worried some researchers because the vaccine, made in monkey cells, was found in 1960 to be contaminated with a monkey virus called simian virus 40, or SV40.
28.
The researchers, who reported their findings at the opening session of a scientific meeting here, said the simian virus was closely related to HIV-1, the type of AIDS virus that has caused the overwhelming majority of cases in the world.
29.
Hopes for a vaccine against AIDS were set back at the 12th World AIDS Conference here Thursday when researchers reported that a vaccine made from a weakened simian virus and injected into monkeys has caused the disease it was designed to prevent.
30.
Researchers measuring the rate of genetic change in HIV, the virus that causes AIDS, found the current strains originated from a common ancestor that first evolved from a simian virus in southwest Africa between 1915 and 1941, with 1931 the most likely year.
