| 21. | Although PLC prefers to act on phosphatidylcholine, it also shows weak catalytic activity with sphingomyelin and phosphatidylinositol.
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| 22. | In the intestinal tract cholesterol and sphingomyelin are co-exiting in lipid vesicles, liposomes and micelles.
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| 23. | The structure of sphingomyelin was first reported in 1927 as N-acyl-sphingosine-1-phosphorylcholine.
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| 24. | Sphingomyelin with set chain length, such as palmitoylsphingomyelin with a saturated 16 acyl chain, is available commercially.
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| 25. | In this case, a fatty molecule, sphingomyelin, accumulates because patients lack an enzyme needed to degrade it.
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| 26. | Sphingomyelin obtained from natural sources, such as eggs or bovine brain, contains fatty acids of various chain length.
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| 27. | It occurs in many lipid mixtures combining cholesterol with a phospholipid and / or sphingolipids e . g . sphingomyelin.
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| 28. | Fluoxetine has been shown to inhibit acid sphingomyelinase, a key regulator of ceramide levels which derives ceramide from sphingomyelin.
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| 29. | It is also understandable that considerable amount of dietary sphingomyelin is delivered into the colon and excreted in the feces.
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| 30. | One category termed a glycerophospholipid and the other a sphingomyelin, or more specifically within the sphingomyelin class, a sphingophospholipid.
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