| 21. | "' Palmitoyl-CoA "'is an acyl-CoA thioester used in the biosynthesis of sphingosine:
|
| 22. | Recent research indicates that sphingosine-1-phosphate ( S1P ) signaling is an important regulator of vascular smooth muscle contraction.
|
| 23. | Sphingosine-1-phosphate ( S1P ) signaling also aides in pericyte recruitment by communication through G protein-coupled receptors.
|
| 24. | The encoded enzyme is responsible for conversion of the sphingosine 1-phosphate ( S1P ) degradation product hexadecenal to hexadecenoic acid.
|
| 25. | Without RhoA binding, lipids such as arachidonic acid or sphingosine phosphorylcholine can increase ROCK1 activity 5-to 6-fold.
|
| 26. | It has been reported that GPR6 is both constitutively active but in addition is further activated by sphingosine-1-phosphate.
|
| 27. | The systematic name of this enzyme class is "'acyl-CoA : sphingosine N-acyltransferase " '.
|
| 28. | The systematic name of this enzyme class is " UDP-galactose : sphingosine 1-beta-galactosyltransferase ".
|
| 29. | BAF312 may be more selective in the particular sphingosine-1-phosphate receptors ( 8 in number ) that it modulates.
|
| 30. | It is important to note that since sphingosine exerts surfactant activity, it is one of the sphingolipids found at lowest cellular levels.
|
