Furthermore, researchers are also aiming to elucidating the molecular mechanisms involved in copy number variations as it may reveal essential information regarding structural variations in general.
22.
Another advantage is that CAPP-Seq can not only detect point mutations but it can also detect indels, structural variations, and copy number variations.
23.
The future advancement in technologies and large database efforts will help lead the way to better quality studies and a much better understanding of human genome structural variation.
24.
As shown in Figure 1, four common structural variations discovered in genome-wide association studies ( GWAS ) studies have pointed to the high turnout of schizophrenia.
25.
In particular, more distant atoms within corresponding features are exponentially downweighted to reduce the effects of noise introduced by loop mobility, helix torsions, and other minor structural variations.
26.
CNVs are the most common type of structural variation in the genome, consisting of deletions and duplications of DNA that range in size from a kilobase to a few megabases.
27.
Alternative RNA splicing of 8 of them significantly increases structural variations of fsTnT . Two variable regions of the fsTnT protein are generated by alternative splicing ( Fig . 3 ).
28.
"Detection of Genomic Structural Variations using Next Generation DNA Sequencing is a study that will examine potential benefits of a new technology called next-generation DNA sequencing to detect changes in chromosomes.
29.
Afterwards, Diabelli is barely recognizable until Variation 15, the second structural variation, a brief, lightweight piece conspicuously inserted between several of the most powerful variations ( Nos . 14, 16 and 17 ).
30.
Studies by Dougherty and coworkers confirmed that cation-? interactions are important for binding and activating nAChR by making specific structural variations to a key tryptophan residue and correlating activity results with cation-? binding ability.
