Subthalamic nucleus cells can then send more activating signals to some parts of the globus pallidus internus and substantia nigra pars reticulata.
26.
However, for patients for whom DBS is not feasible, ablation of the subthalamic nucleus has been shown to be safe and effective.
27.
When movement adjustment is required, striatal inhibitory GABAergic axons are sent to the "'lateral globus pallidus, "'decreasing inhibition of the subthalamic nucleus.
28.
This suggests that the subthalamic nucleus is plastic enough to adapt to small amounts of damage in order to resume normal function.
29.
The GPe and VP send a GABAergic projection to the subthalamic nucleus, which then sends glutamatergic projections to the GPi and SNpr.
30.
The GPe projects to the subthalamic nucleus ( STN ), which then projects back to the GPi and GPe via excitatory, glutaminergic pathways.