The N-terminal segment has an actin binding domain and the C-terminal segment has a + TIP binding site as well as microtubule interacting domains.
22.
The neurons in the core, as compared to the neurons in the shell, have an increased density of dendritic spines, branch segments, and terminal segments.
23.
The overall topology resembles a vise, with the central core of the protein at the base and the N-and C-terminal segments on the sides.
24.
The anterior and posterior thorax and the first and fourth abdominal segments are yellow, abdominal segments 2 to 3 are orange, and the terminal segments are black.
25.
The shape varies from fusiform with inconspicuous projections on posterior segments to short, broad, and flattened with conspicuous dorsal and lateral plumose projections especially on the terminal segment.
26.
These structural features provide a rationale for the phenomenon of ?-complementation, where the deletion of the amino-terminal segment results in the formation of an inactive dimer.
27.
The neurons in the shell, as compared to the core, have a lower density of dendritic spines, less terminal segments, and less branch segments than those in the core.
28.
Head, thorax, and abdomen orange-yellow; antenn?brown, the shaft whitish above; palpi, pectus, legs, and ventral surface of abdomen except terminal segment brown.
29.
While the central core domain ( motif A in GNATs ) is involved in acetyl-CoA binding and catalysis, the N-and C-terminal segments assist in binding histone substrates.
30.
Along with Asp-protonation, lower pH also leads to conformational switch in cathepsin-D : the N-terminal segment of the protease moves out of the active site as pH drops.