Following a declination or total extinction in response to a previously therapeutic dose of an antidepressant, the issue is clinically addressed as stemming from tolerance development.
22.
On pseudoephedrine, the only over-the-counter decongestant, the American Academy of Family Physicians has recently reported that the range between a therapeutic dose and toxic dose is narrow.
23.
Trace amounts of theophylline are also found in brewed tea, although brewed tea provides only about 1 mg / L, which is significantly less than a therapeutic dose.
24.
The generally accepted half-life for a therapeutic dose was not found appropriate in intoxicated patients and would underestimate the time required to reach a safe concentration of the drug.
25.
In clinical human trials with increasing dosages, vanoxerine has shown to have a highly favourable therapeutic index, showing no side effects at concentrations much higher than the therapeutic dose.
26.
In early 1941, Hertz administered cyclotron produced a I-130-I-131 mixture as a therapeutic dose to the first human patient at MGH, to a patient with Graves hyperthyroidism, or Graves'disease.
27.
Regardless of the initial method of preparation, multiple donations may be combined into one container using a sterile connection device to manufacture a single product with the desired therapeutic dose.
28.
The 25 �g of atropine present in each 2?mg Lomotil tablet is 1 / 40 of the standard therapeutic dose of atropine via the oral route for normal anticholinergic uses.
29.
The link was strengthened by experiments in the 1970s which suggested that the binding affinity of antipsychotic drugs for D 2 dopamine receptors seemed to be inversely proportional to their therapeutic dose.
30.
But some limits that have been mentioned by industry include analytical detection levels such as 10 PPM, biological activity levels such as 1 / 1000 of the normal therapeutic dose and organoleptic levels.
