Dietary acids and bases are not going to effect the acid base chemistry of a human unless it is in a toxic dose.
22.
A compound with a wide therapeutic index ( greater than five ) exerts its desired effect at a dose substantially below its toxic dose.
23.
Inhalation of these gases neutralizes oxygen absorption by the bloodstream and can be fatal within a few minutes if toxic dose levels are exceeded.
24.
The median toxic dose for humans ranges from 10 to 1000 micrograms per kilogram when ingested and is 3.3 micrograms per kilogram when inhaled.
25.
A compound with a narrow therapeutic index ( close to one ) exerts its desired effect at a dose close to its toxic dose.
26.
You may also want to ask about the so-called " therapeutic range, " that is, how far a toxic dose is from the safe, effective dose.
27.
"Because there's no way to tell the strength of home-made GHB, what might be a safe dose today could produce a toxic dose tomorrow, " he said.
28.
He said children would have to swallow 50 grammes of 1, 000 parts per million fluoridated toothpaste at one sitting to suffer from a probable toxic dose.
29.
On pseudoephedrine, the only over-the-counter decongestant, the American Academy of Family Physicians has recently reported that the range between a therapeutic dose and toxic dose is narrow.
30.
In addition to the other side effects, the WHO researchers were concerned about gossypol's toxicity : the toxic dose in primates is less than 10 times the contraceptive dose.
