| 21. | With a high value, proton transfer in the transition state is almost complete.
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| 22. | One way that enzymatic catalysis proceeds is by stabilizing the transition state through electrostatics.
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| 23. | An example of the late transition state is bromination.
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| 24. | Transition state for the Narasaka Prasad reduction showing the reasons for the observed diastereoselectivity
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| 25. | An example of the early transition state is chlorination.
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| 26. | Thus the energy of the transition state is mostly polarization energy of the solvent.
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| 27. | Correlation diagrams can then be used to predict the height of transition state barriers.
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| 28. | Transition state theory fails for some reactions at high temperature.
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| 29. | The formation of this oxyanion hole stabilizes the transition state of the enzyme-catalyzed reaction.
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| 30. | Nonetheless, cyclic transition states are frequently invoked to interpret diastereoselectivity.
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