About half, as judged by their sequence of DNA letters, are similar to genes found in other bacteria, particularly the fellow spirochete that causes Lyme disease, and the rest are unique to Treponema pallidum.
22.
The new data will also include the nearly complete genome of Treponema pallidum, which causes syphilis, and partial sequences of the tuberculosis bacillus, the cholera bacterium and the second chromosome of the malaria parasite.
23.
Despite the extreme age of the spirochetes, which have existed for well over 100 million years, Treponema pallidum presumably learned only recently how to infect humans, a host with a mere 100, 000-year ancestry.
24.
TIGR followed these accomplishments with the genomes of the pathogenic bacteria " Borrelia burgdorferi " ( which causes Lyme Disease ) in 1997 and " Treponema pallidum " ( which causes syphilis ) in 1998.
25.
Syphilis is now relatively rare, but the tertiary stage can cause diffuse glossitis and atrophy of lingual papillae, termed " syphlitic glossitis ", It is caused by Treponema pallidum and is a sexually transmitted infection.
26.
With Paul Blocq he was the first to describe senile plaques and with Romanian neurologist Ion Minea confirmed in 1913 Hideyo Noguchi's discovery of " Treponema pallidum " in the brain in patients with general paresis.
27.
Like other spirochetes, such as " Treponema pallidum " ( the agent of syphilis ), " B . burgdorferi " has an axial filament composed of flagella which run lengthways between its cell wall and outer membrane.
28.
Syphilis ( caused by infection with " Treponema pallidum " ) is passed from person to person through direct contact with a syphilis sore; these occur mainly on the external genitals, or in the vagina, anus, or rectum.
29.
Three or four bouts of fever were enough to kill the temperature-sensitive syphilis bacteria ( " Spirochaeta pallida " also known as " Treponema pallidum " ) . " P . vivax " infections were terminated by quinine.
30.
The " "'Treponema pallidum " particle agglutination assay "'( also called "'TPPA "'test ) is an indirect agglutination assay used for detection and titration of antibodies against the causative agent of syphilis, " Treponema pallidum " subspecies " pallidum ".
