In 1909, examining the lungs of guinea pigs experimentally infected with " Trypanosoma cruzi ", Carlos Chagas described parasitic forms that linked the pulmonary cycle of the trypanosome.
22.
By 1903, researchers had determined that sleeping sickness was caused by a trypanosome, a parasite that lived and multiplied extracellularly in the blood and tissue fluids of its human hosts.
23.
If eflornithine is prescribed to a patient with Human African trypanosomiasis caused by a trypanosome that contains a mutated or ineffective TbAAT6 gene, then the medication will be ineffective against the disease.
24.
Trypanosomes endocytose the secreted form of APOL1; APOL1 forms pores on the lysosomal membranes of the trypanosomes which causes in influx of chloride, swelling of the lysosome and lysis of the trypanosome.
25.
In 1927, Hoare left for an extended secondment to the Uganda Medical Service in Entebbe, Uganda, where he spent two years investigating the lifecycle of the crocodile trypanosomes, Trypanosome Grayi.
26.
""'Trypanosoma suis " "'is a species of excavate trypanosome in the genus " Trypanosoma " that causes one form of the surra disease in animals.
27.
All " T . b . gambiense " are resistant to killing by a serum component trypanosome lytic factor ( TLF ) of which there are two types : TLF-1 and TLF-2.
28.
Tidwell said $ 10 million would go to pay for human trials by Immtech in central Africa for a compound, DB-289, that after three or four oral doses has eliminated the trypanosome parasite, which causes sleeping sickness, from animals'blood.
29.
The dominant parasites were " Theileria " species, " trypanosome was isolated from a nyala, wild-caught in Mozambique, which was diagnosed and found as akin to " Trypanosoma vivax ", based on biological, morphological and molecular data.
30.
Tsetse flies have an arsenal of immune defenses to resist each stage of the trypanosome infectious cycle, and thus are relatively refractory to trypanosome infection Among the host flies defenses is the production of hydrogen peroxide, a reactive oxygen species that damages DNA . These defenses limit the population of infected flies.
