| 31. | Various stress-induced elevations of ACTH are blunted in the Avpr1b knockout mouse.
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| 32. | ACTH receptor is primarily found in the zona fasciculata of the human adrenal cortex.
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| 33. | Aldosterone synthase normally is not ACTH sensitive, and only activated by angiotensin II.
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| 34. | Reducing ACTH synthesis, it improves the sexual drive of rats under stressing conditions.
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| 35. | ACTH is also produced by corticotropes in the pars distalis of the equine pituitary.
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| 36. | There are few alternative treatments and none are as effective as ACTH, experts say.
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| 37. | Conversely, chronically elevated ACTH levels occur in primary adrenal insufficiency ( e . g.
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| 38. | In turn, ACTH directs the adrenal cortex to secrete glucocorticoids, such as cortisol.
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| 39. | The ACTH receptor plays a role in glucose metabolism when expressed in white adipose cells.
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| 40. | ACTH receptor activation also influences immune function.
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