In a few rare circumstances, more serious ( but reversible ) conditions have been seen, such as adrenal insufficiency and hepatic encephalopathy.
32.
Abrupt discontinuation can result in adrenal insufficiency; and / or steroid withdrawal syndrome ( a rebound effect in which exaggerated symptoms return ).
33.
Waterhouse Friderichsen syndrome ", a massive, usually bilateral, hemorrhage into the adrenal glands caused by fulminant meningococcemia, adrenal insufficiency, and disseminated intravascular coagulation.
34.
Adrenocorticotropic hormone ( ACTH ) deficiency leads to adrenal insufficiency, a lack of production of glucocorticoids such as cortisol by the adrenal gland.
35.
In order to check for Addison s Disease, the auto-immune type of primary adrenal insufficiency, labs should be drawn to check 21-hydroxylase autoantibodies.
36.
The first reported case was in 1962, with a 22-year-old who died of adrenal insufficiency 14 months after giving birth to her second child.
37.
Approximately one-quarter of patients with ONH have adrenal insufficiency, meaning they do not produce enough cortisol on a daily basis or in stressful situations.
38.
Adrenal insufficiency can also occur when the hypothalamus or the pituitary gland does not make adequate amounts of the hormones that assist in regulating adrenal function.
39.
Due to the absence of adrenal cortex, the condition causes extreme symptoms of adrenal insufficiency at birth due to very low levels of aldosterone and cortisol.
40.
Earlier accounts have said that Kennedy was first known to have adrenal insufficiency in 1947, but there are strong hints that he was treated many years earlier.