| 31. | "' 2-Iodoacetamide "'is an alkylating agent used for peptide mapping purposes.
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| 32. | Its toxicity correlates to its ability as an alkylating agent, which will modify cysteine residues in proteins.
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| 33. | Inside cells, amifostine detoxifies reactive metabolites of platinum and alkylating agents, as well as scavenges free radicals.
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| 34. | Diethyl sulfate is used as an alkylating agent to prepare ethyl derivatives of phenols, amines, and thiols.
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| 35. | Allyl bromide is an alkylating agent used in synthesis of polymers, pharmaceuticals, allyls and other organic compounds.
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| 36. | Methylation of the MGMT promoter in gliomas is a useful predictor of the responsiveness of tumors to alkylating agents.
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| 37. | As an alkylating agent, it is useful in the manufacture of pharmaceuticals and pesticides, such as mustard oil.
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| 38. | Cyclophosphamide and the related nitrogen mustard derived alkylating agent ifosfamide were developed by Norbert Brock and ASTA ( now FDA.
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| 39. | It acts as an alkylating agent causing intra-strand and inter-strand cross-links between DNA bases.
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| 40. | Secondary alkylating agents also react, but tertiary ones are usually too prone to side reactions to be of practical use.
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