That is, the stimulating effects of alcohol ( i . e ., euphoria, sociality, energy ) are more prevalent as BAC rises ( i . e ., ascending limb ), while alcohol's sedative effects ( i . e ., relaxation, nausea, headaches ) are experienced most strongly as BAC falls ( i . e ., descending limb ).
32.
As ions leave the lumen via the Na-K-2Cl symporter and the Na-H antiporter, the concentration becomes more and more hypotonic until it reaches approximately 100-150 mOsm / L . The ascending limb is also called the diluting segment of the nephron because of its ability to dilute the fluid in the loop from 1200 mOsm / L to 100 mOsm / L.
