The biotin-binding properties of avidin were exploited during the development of idrabiotaparinux, a long-acting low molecular weight heparin used in the treatment of venous thrombosis.
32.
This antibody has also been treated with biotin, a Vitamin-D derivative that acts like a kind of molecular Velcro when exposed to avidin, a protein derived from eggs.
33.
Further amplification can be achieved if the secondary antibody is conjugated to several biotin molecules, which can recruit complexes of avidin-, streptavidin-or NeutrAvidin protein-bound enzyme.
34.
While working to characterize the yeast growth factor that would become known as biotin, Snell and coworkers discovered the egg white protein avidin, which binds biotin with extremely high affinity.
35.
By adding a biotin moiety to the idraparinux molecule, idrabiotaparinux was formed; its anticoagulant activity in the setting of a bleeding event can be reversed through an intravenous infusion of avidin.
36.
While there are some non-covalent interactions that may survive 2D-PAGE ( biotin-( strept ) avidin, for example ) I wouldn't rely on this happening.
37.
The thermal stability and biotin binding activity of avidin are of both practical and theoretical interest to researchers, as avidin's stability is unusually high and avidin is an antinutrient in human food.
38.
The thermal stability and biotin binding activity of avidin are of both practical and theoretical interest to researchers, as avidin's stability is unusually high and avidin is an antinutrient in human food.
39.
The thermal stability and biotin binding activity of avidin are of both practical and theoretical interest to researchers, as avidin's stability is unusually high and avidin is an antinutrient in human food.
40.
The natural function of avidin in eggs is not known, although it has been postulated to be made in the oviduct as a bacterial growth-inhibitor, by binding biotin helpful for bacterial growth.
