| 31. | Another important contribution of Horowitz was his 1945 proposal on the backward evolution of biosynthetic pathways.
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| 32. | Tabtoxin biosynthesis branches off from the lysine biosynthetic pathway before the formation of diaminopimelate ( DAP ).
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| 33. | Other biosynthetic pathways likely exist, but the enzymes catalyzing these reactions have not yet been identified.
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| 34. | There are two distinct lysine biosynthetic pathways : the diaminopimelic acid pathway and the ?-aminoadipate pathway.
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| 35. | Biosynthetic pathways are often highly regulated such that building-blocks are synthesized only when supplies are low.
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| 36. | FPPS, a geranyltranstransferase, catalyzes reactions ( shown with red arrows ) central to many biosynthetic pathways.
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| 37. | In prokaryotes, biosynthetic pathways exist for the tetracyclic steroid framework ( e . g . in hopanoid framework.
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| 38. | These two sites catalyze the last two steps of the de novo uridine monophosphate ( UMP ) biosynthetic pathway.
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| 39. | HMG CoA reductase occurs early in the biosynthetic pathway and is among the first committed steps to cholesterol formulation.
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| 40. | Because all amino acids except glycine are chiral, biosynthetic pathways must generate the correct isomer with high fidelity.
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