This toxin is considered the main cause of CDAD . TcdA damages intestinal villous tips, which disrupts the brush border membrane, leading to cell erosion and fluid leakage from the damaged area.
32.
In intestinal cells, the microvilli are referred to as striated border and are protoplasmic extensions contrary to villi which are submucosal folds, while in the kidneys, microvilli are referred to as brush border.
33.
A ferric reductase enzyme on the enterocytes'brush border, Dcytb, reduces ferric Fe3 + to Fe2 + . " Does this mean the body can absorb ferric ions, by converting them to ferrous ions?
34.
GCPII is mainly expressed in four tissues of the body, including prostate epithelium, the proximal tubules of the kidney, the jejunal brush border of the small intestine and ganglia of the nervous system.
35.
Ezetimibe reduces blood cholesterol by acting at the brush border of the small intestine and inhibiting the absorption of cholesterol, leading to a decrease in the delivery of intestinal cholesterol to the liver.
36.
The well-characterized mammalian proteins are found in renal ( IIa isoform ) and intestinal ( IIb isoform ) brush border membranes and are about 640 amino acyl residues long with 8-12 putative TMSs.
37.
When the glucose concentration in the lumen of the small intestine goes above 30mM, such as occurs in the fed-state, GLUT2 is up-regulated at the brush border membrane, enhancing the capacity of glucose transport.
38.
Enteropeptidase is a type II transmembrane serine protease ( TTSP ) localized to the brush border of the duodenal and jejunal mucosa and synthesized as a zymogen, proenteropeptidase, which requires activation by duodenase or trypsin.
39.
Enteropeptidase is a serine protease ( ) consisting of a disulfide-linked heavy-chain of 82-140 kDa that anchors enterokinase in the intestinal brush border membrane and a light-chain of 35 62 kDa that contains the catalytic subunit.
40.
The products of digestion of alpha-amylase and alpha-dextrinase, along with dietary disaccharides are hydrolyzed to their corresponding monosaccharides by enzymes ( maltase, isomaltase, sucrase and lactase ) present in the brush border of the small intestine.
